My research on the neurophysiological mechanisms underlying psychiatric disorders began during my diploma thesis at the Psychiatric Clinic of the University Hospital Benjamin Franklin, Free University Berlin. While I started with the examination of individuals with generalized anxiety disorder, my psychiatric research primarily focuses on the neural mechanisms underlying the clinical symptoms in schizophrenia. Currently, we are conducting studies on multisensory speech processing in this patient group. My more recent research also includes studies on speech processing in persons with cochlear implants.
Key Publications
Senkowski D, Linden M, Zubrägel D, Bär T, Gallinat J (2003). Evidence for disturbed cortical signal processing and altered serotonergic neurotransmission in Generalized Anxiety Disorder. Biological Psychiatry 53, 304-314 (PDF)
Gallinat J, Winterer G, Herrmann CS, Senkowski D (2004). Reduced oscillatory gamma responses in unmedicated schizophrenic patients indicated impaired frontal network processing. Clinical Neurophysiology 115: 1863-1874 (PDF)
Gallinat J, Mulert C, Bajbouj M, Herrmann WM, Schunter J, Senkowski D, et al. (2002). Frontal and temporal dysfunction of auditory stimulus processing in schizophrenia. Neuroimage 17: 110-127 (PDF)
Support by a NARSAD Young Investigator Award and the Young Investigator Research Fund of the University Medical Center Hamburg-Eppendorf is gratefully acknowledged.
Evoked gamma-band responses at frontal regions are reduced in umedicated schizophrenics compared to healthy control subjects. In addition, the magnitude of oscillatory activity was linked to clinical parameters in the patient group. This suggests a crucial role of oscillatory for the pathology of schizophrenia (Adapted from Gallinat et al. 2004).